Population with Han ancestry in northern China.Material and methodsSubjectsstudy. The — различия между версиями

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The control group was composed of subjects who did not have cerebrovascular [https://www.medchemexpress.com/Geldanamycin.html Geldanamycin manufacturer] diseases themselves, and no family history of cerebrovascular diseases for a minimum of three generations. Single markers in association with the disease were assessed using 2 tests in Haploview Version 4.2 (Broad Institute, Cambridge, MA, USA). Odds ratios (ORs) and 95  confidence intervals (CIs) were calculated using logistic regression analysis. Statistical analysis was performed using by SPSS version 15.0 statistical software (SPSS, Inc., Chicago, IL, USA). A value of P [https://www.ncbi.nlm.nih.gov/pubmed/25957400 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25957400] were excluded from this study. The control group was composed of subjects who did not have cerebrovascular diseases themselves, and no family history of cerebrovascular diseases for a minimum of three generations. All the subjects in this study were from different families of Han ethnicity whose families have lived in the Northeastern part of China, including Heilongjiang, Jilin and Liaoning, for more than 3 generations. This study was approved by the Institutional Review Board of the Fourth Affiliated Clinical Hospital of Harbin Medical University and each participant provided written informed consent.DNA extraction and genotypingData are presented as mean ?standard deviation or number (percentage).
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The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010.Population with Han ancestry in northern China.Material and methodsSubjectsstudy. The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010. All cases were diagnosed using the Fourth edition of Cerebrovascular Disease Diagnostic Standards [11]. Patients who had endocrine related diseases, metabolic disorders, tumors, and cerebral hemorrhage [https://www.ncbi.nlm.nih.gov/pubmed/25957400 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25957400] were excluded from this study.Population with Han ancestry in northern China.Material and methodsSubjectsstudy. The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010. All cases were diagnosed using the Fourth edition of Cerebrovascular Disease Diagnostic Standards [11]. Patients who had endocrine related diseases, metabolic disorders, tumors, and cerebral hemorrhage [https://www.ncbi.nlm.nih.gov/pubmed/25957400 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25957400] were excluded from this study. The control group was composed of subjects who did not have cerebrovascular diseases themselves, and no family history of cerebrovascular diseases for a minimum of three generations. All the subjects in this study were from different families of Han [http://mythailand.ru/album/471096 Al effects of fucoidan in sufferers with chronic hepatitis C virus] ethnicity whose families have lived in the Northeastern part of China, including Heilongjiang, Jilin and Liaoning, for more than 3 generations. This study was approved by the Institutional Review Board of the Fourth Affiliated Clinical Hospital of Harbin Medical University and each participant provided written informed consent.DNA extraction and genotypingData are presented as mean ?standard deviation or number (percentage). Hardy-Weinberg equilibrium (HWE) testing was carried out for all 7 [https://www.ncbi.nlm.nih.gov/pubmed/26740125 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26740125] SNPs. Single markers in association with the disease were assessed using 2 tests in Haploview Version 4.2 (Broad Institute, Cambridge, MA, USA). Odds ratios (ORs) and 95  confidence intervals (CIs) were calculated using logistic regression analysis. Statistical analysis was performed using by SPSS version 15.0 statistical software (SPSS, Inc., Chicago, IL, USA). A value of P

Версия 02:38, 20 апреля 2019

The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010.Population with Han ancestry in northern China.Material and methodsSubjectsstudy. The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010. All cases were diagnosed using the Fourth edition of Cerebrovascular Disease Diagnostic Standards [11]. Patients who had endocrine related diseases, metabolic disorders, tumors, and cerebral hemorrhage PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25957400 were excluded from this study.Population with Han ancestry in northern China.Material and methodsSubjectsstudy. The SNPs rs9579646 and rs4147064 were selected because they showed weak association with stroke in Israeli [2] and middle European populations [13], and rs4073259 was found to be associated with stroke in a preliminary study [12].Statistical analysisThe subjects included in this study were patients diagnosed with cerebral infarction from three hospitals including the Second Affiliated Hospital of Harbin Medical University, the Forth Affiliated Clinical Hospital of Harbin Medical University, and the First Affiliated Hospital of Harbin Medical University from October 2004 to May 2010. All cases were diagnosed using the Fourth edition of Cerebrovascular Disease Diagnostic Standards [11]. Patients who had endocrine related diseases, metabolic disorders, tumors, and cerebral hemorrhage PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25957400 were excluded from this study. The control group was composed of subjects who did not have cerebrovascular diseases themselves, and no family history of cerebrovascular diseases for a minimum of three generations. All the subjects in this study were from different families of Han Al effects of fucoidan in sufferers with chronic hepatitis C virus ethnicity whose families have lived in the Northeastern part of China, including Heilongjiang, Jilin and Liaoning, for more than 3 generations. This study was approved by the Institutional Review Board of the Fourth Affiliated Clinical Hospital of Harbin Medical University and each participant provided written informed consent.DNA extraction and genotypingData are presented as mean ?standard deviation or number (percentage). Hardy-Weinberg equilibrium (HWE) testing was carried out for all 7 PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26740125 SNPs. Single markers in association with the disease were assessed using 2 tests in Haploview Version 4.2 (Broad Institute, Cambridge, MA, USA). Odds ratios (ORs) and 95 confidence intervals (CIs) were calculated using logistic regression analysis. Statistical analysis was performed using by SPSS version 15.0 statistical software (SPSS, Inc., Chicago, IL, USA). A value of P