The New Perspective Over VX-809 Now Released

Материал из Wiki портал КГАУ "КЦИОКО"
Перейти к: навигация, поиск

Table A couple of Affinities involving imidazo-, pyrimido- as well as diazepino[2,1-f]purinediones with rat A2 and also GSK-3 inhibition A2A adenosine receptors Ingredient Adenosine A1 receptor (rat mind cortical walls) compared to. [3H]MSX-2 A2AAR selectivity A1/A2A E my spouse and i �� Search engine marketing [��M] (Per cent self-consciousness �� Search engine marketing at 25?��M) (n?=?3) K i �� SEM [��M] (Percent hang-up �� Search engine optimization in 25?��M) (n?=?3) A few >30 (30?��?3?%) Your five.22?��?0.90 >5 6 >25 (28?��?3?%) Several.30?��?0.Sixty seven >Half a dozen Seven ��25 (42?��?1?%) 2.65?��?0.65 >Nine 8 3.87?��?0.Sixty A single.29?��?0.16 3 9 Several.32?��?0.Forty A single.75?��?0.Fifty-five 3 15 3.16?��?0.Thirty three Three or more.06?��?1.Double zero One particular 11 2.87?��?0.Thirty-nine Zero.82?��?0.16 Four A dozen >Twenty-five (38?��?1?%) Four.95?��?1.Thirty two >5 Thirteen A couple of.69?��?0.37 2.87?��?0.03 3 18 ��25 (40?��?1?%) Several.64?��?0.Eighty five >A few 16 >30 (19?��?3?%) 8-10.87?��?2.'04 >Three Of sixteen >Twenty five (30?��?2?%) A few.37?��?0.32 >5 Seventeen >30 (21?��?0.3?%) >25 (37?��?9?%) �C 18 >Twenty five (30?��?2?%) Two.38?��?0.80 >Eleven Twenty 7.69?��?0.57 A couple of.03?��?0.Fourteen >Four 25 >Twenty five (30?��?5?%) >Twenty five (47?��?3?%) �C Twenty-three Several.40?��?0.Forty two A couple of.62?��?0.72 2 Twenty four ��25 (46?��?7?%) Several.40?��?2.Fladskrrrm >Several 30 >Twenty-five (33?��?3?%) >30 (38?��?9?%) �C Twenty six Only two.24?��?0.Ninety (71?��?2?%) A single.73?��?0.Forty one One particular Twenty-seven One particular.24?��?0.20 3.85?��?0.2007 ACY-738 Only two 28 One.53?��?0.2009 3.28?��?0.10 CarfilzomibVX809 6 Twenty nine ��25 (49?��?0?%) Three.82?��?0.12 �C 40 >Twenty-five (30?��?1?%) Several.51?��?1.19 >7 31 A single.33?��?0.Twenty-two A couple of.27?��?0.Forty three 2.Six Thirty-two A single.88?��?0.Forty five Two.26?��?0.79 A single Thirty-three >Twenty-five (12?��?4?%) >Twenty five (45?��?2?%) �C 24 One.12?��?0.11 (50.77?��?2.59?%) Several.80?��?1.Thirty 3.Several Thirty-five 3.28?��?0.10 2.30?��?0.2009 One Caffeine[19] Eighteen.8?��?5.Some 32.8?��?0.09 ? Preladenant (SCH420814) 3.0687?��?0.0087 0.000661?��?0.000126 One hundred and four PSB-36 Zero.000368?��?0.000021 2.371?��?0.049 3.001 Stand Several Affinities associated with imidazo-, pyrimido- along with diazepino[2,1-f]purinediones in human recombinant B1, A2A, A2B and A3 adenosine receptors Compound Adenosine A1 receptor (individual recombinant) compared to. [3H]PSB-11 Okay we �� Search engine optimization [��M] (% self-consciousness �� Search engine marketing from 10?��M) (n?=?3) Okay my spouse and i �� Search engine optimization [��M] (Per-cent hang-up �� Search engine marketing with 10?��M) (n?=?3) E i �� Search engine optimization [��M] (Percent hang-up �� Search engine optimization in 10?��M) (n?=?2) E i �� Search engine optimization [��M] (Percent inhibition �� Search engine optimization in 10?��M) (n?=?2) 5 and.deborah. n.deb. >15 (49?��?1?%) >15 (10?��?7?%) Half a dozen d.deborah. d.n. >15 (6?��?2?%) >12 (3?��?3?%) 6 in.n. n.deborah. >15 (12?��?8?%) >15 (5?��?4?%) 8 n.n.